Coronavirus Protein Microarray
Comparison of different lab-tests
Multiplexed. Simultaneously detect serum IgG/IgM and profile the immune responses against many coronaviral proteins.
Accurate. Since we compare many proteins from SARS-CoV-2, SARS-CoV, and MERS-CoV, the false negative or non-specific bindings can be evaluated. Also, the combination of multiple markers always can help the specificity and accuracy for the diagnosis.
Flexible. We can include the protein with common mutations that observed in the clinical samples and provide a deeper view of the impact of SARS-CoV-2 mutations. For the clinical applications, it is also flexible to discover and combine different markers for the diagnosis, prognosis, and severity classifications.
Sensitive. Only need 1 microliter serum the assay which is less than a drop of blood. In a microliter, we can acquire numerous data information for the research, clinical, and epidemical uses.
Specific. The protein microarray is a useful platform to show the specificity of the biologicals. The coronavirus protein array will speed up the process of developing biologicals for both detection and medical use.
Highly sensitive. Can detect 50ng antibodies which is 1000x lower than ELISA method.
Test 33 COVID-19 positive serum and 32 positive (sensitivity rate 97.0%)
Test 35 control serum and 34 negative (specificity rate 97.1%)