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The availability of recombinant allergenic molecules has enhanced IgE antibody assay performance in a several ways

  • It has permitted an increased analytical sensitivity by supplementing extracts that are deficient in a particular allergen specificity.

  • There is an increase in analytical specificity when selected molecules are used to detect IgE antibodies. 

  • Molecular allergens allow the identification of cross-reactivity. 

  • Selected molecules define IgE antibodies as a marker of a genuine primary sensitization.

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